Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae1ceb9a3655ff18e2f217d8ee8fc3a0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0667 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
filingDate |
2016-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36ca128563702f701e779c4c2a871319 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6fe089da65654b83cc32e87ba2748f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f609d53d41ebfd3b5d524b2fbeed91b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_900a3869df5c7c5af2d1452fae4a4a20 |
publicationDate |
2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-108348555-A |
titleOfInvention |
Cell expansion methods and therapeutic compositions |
abstract |
The present invention relates to methods for the production of mesenchymal stem cells (MSCs), in particular to methods for the large-scale production of MSCs (eg, allogeneic MSCs) for the treatment of various diseases in humans and other animals. The present invention also relates to methods allowing selection of preferred donor cells suitable for large-scale production of MSCs. The invention also relates to purified MSCs prepared by the method of the invention. The invention also relates to the use of platelet lysates in methods for the preparation of MSC cultures and the preparation of extracellular matrix-enriched secretions. The present invention also relates to methods for the preparation of compositions comprising one or more components secreted from cultured MSCs, said components having improved stability characteristics. The present invention also relates to methods of treating inflammatory conditions, including alleviating their pain, by administering conditioned medium enriched in high molecular weight glycoconjugates, and to treating inflammatory conditions by administering conditioned medium enriched in high molecular weight glycoconjugates Approaches to neuropathic pain. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111073857-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110106142-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110106142-A |
priorityDate |
2015-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |