| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L2203-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-179
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L71-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0051 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate |
2016-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47e913ff7c39a7034bd0e05bff6e3f78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14969d10e87b4c91d37223c0f1840366 |
| publicationDate |
2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108348462-A |
| titleOfInvention |
Stabilized protein composition |
| abstract |
The present invention discloses stable pharmaceutical formulations and drug delivery devices. In certain embodiments, the drug delivery device contains a reservoir that, when implanted in a patient, is in partial contact with the tissue environment. The reservoir is kept in contact with the environment via a porous structure in the housing of the delivery device. The reservoir houses a therapeutic biomolecule in combination with a second molecule for stabilizing the therapeutic biomolecule and limiting the solubility of the therapeutic biomolecule, thereby controlling therapeutic biomolecule dissolution amount. The concentration of the soluble therapeutic biomolecule or the size of the surface area of the porous structure controls the rate at which the therapeutic biomolecule is delivered to the target tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291636-B2 |
| priorityDate |
2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |