http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108341914-B

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filingDate 2017-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108341914-B
titleOfInvention Preparation method of amphoteric affinity polymer microspheres with core-shell structure
abstract The invention relates to a preparation method of amphiphilic affinity polymer microspheres with a novel core-shell structure, which comprises the following steps of (a) preparing hydrophobic particle poly (divinylbenzene-co-4-vinylphenylboronic acid) microspheres by a distillation precipitation method; (b) the amphoteric affinity polymer microspheres with the core-shell structure are prepared by a Pickering emulsion dispersion polymerization mode. The invention has the beneficial effects that: (1) the amphiphilic nucleophilic polymer with the core-shell structure, which is prepared by the invention, has hydrophobic surface and hydrophilic interior, can be used for better protection to horseradish peroxidase under a high-temperature condition, so that the horseradish peroxidase has better activity and good enzyme activity. (2) The preparation method does not use a surfactant, overcomes the problem of difficult removal of the traditional surfactant, and provides an effective means for researching the protein denaturation mechanism in the future.
priorityDate 2017-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 45.