http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108341828-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108341828-B |
| titleOfInvention | Process for preparing eribulin and intermediates thereof |
| abstract | The present invention relates to a method for preparing eribulin and an intermediate thereof. Specifically, the present invention relates to the preparation method of the compound of formula 5, R 3 is selected from aldehyde group or OR 1 , n=0 or 1, R 1 is a hydroxyl protecting group, and the hydroxyl protecting group is preferably selected from tert-butyldimethyl group Silyl, tert-butyldiphenylsilyl, p-methoxybenzyl or benzyl. Also provided is a preparation method for the compound of formula 5 for preparing halichondrin and derivatives thereof, such as eribulin. |
| priorityDate | 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.