http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108341775-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-227 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-227 |
filingDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108341775-B |
titleOfInvention | Synthetic method of rebamipide intermediate |
abstract | The invention discloses a key intermediate 2-amino-3- [2 (1) for synthesizing rebamipide H ) -quinolone-4]A novel process for the production of propionic acid. The method comprises the step of reacting aspartic acid with 2-hydroxyquinoline to prepare the rebamipide key intermediate 2-amino-3- [2 (1) H ) -quinolone-4]Propionic acid and p-chlorobenzoyl chloride are condensed to prepare rebamipide. The intermediate synthesis method has the advantages of cheap and easily-obtained raw materials, short reaction steps and good optical purity. 。 |
priorityDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.