http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108329330-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 |
| filingDate | 2017-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108329330-B |
| titleOfInvention | 2-benzyloxy phenyl oxazolopyridine compound and pharmaceutical application thereof |
| abstract | The invention belongs to the field of pharmaceutical chemistry, and relates to a 2-benzyloxy phenyl oxazolopyridine compound shown in a formula I structure and a pharmaceutical application thereof, wherein R, X, Y and Z are consistent with detailed description in the invention content. The compounds can inhibit the activity of sphingomyelin synthase and can be used for preparing small molecule inhibitors of sphingomyelin synthase. The invention provides aA compound shown as a formula I structure or a pharmaceutical composition taking the compound as an effective active ingredient and application thereof in preparing medicaments for preventing and treating diseases caused by abnormal increase of sphingomyelin level; the diseases caused by abnormal increase of sphingomyelin level comprise metabolic syndromes such as atherosclerosis, fatty liver, obesity and type II diabetes. （I）。 |
| priorityDate | 2017-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.