http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108329276-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41cd56d9326625dec7f0865f8146bf95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_737901fa559eeebcbfdd3f6e1797ced5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
| filingDate | 2018-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_981ee97e65afe26b9a92850722fd874e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7b2de8d5a2fa75f01d5b37a8cc25d9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5673676e53ff76a2d23718a8925ba72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03506bcbbd61d722e12d93c498a69795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d31687c5050ce636020a85f251614352 |
| publicationDate | 2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108329276-A |
| titleOfInvention | Heterocyclic derivatives and their preparation and use |
| abstract | The present invention relates to the field of chemical synthesis, in particular to a method for preparing heterocyclic derivative 1 and metal salt 2 thereof. Compound 1 or 2 can be used to prepare antitumor drugs; heterocyclic derivative 1 and its metal derivative 2, compound 3 is deacetylated in methanol solution of ammonia to obtain compound 1; compound 1 obtained in step (1) and MOH is salified to obtain 2; the pure compound 1 or compound 2 prepared by this method is used as raw material to carry out condensation reaction with compound 4 to obtain compound 5; according to the method of the present invention, high-purity compound 1 and original compound 1 which cannot be obtained before can be obtained. The production cost of the unobtainable high-purity metal salt derivative 2, compound 5 is also significantly reduced. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109438423-A |
| priorityDate | 2018-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.