http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108318447-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-359 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-359 |
| filingDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108318447-B |
| titleOfInvention | A method for rapid determination of enantiomeric composition of praziquantel based on near-infrared spectroscopy |
| abstract | The invention discloses a method for detecting the enantiomer content of praziquantel, in particular to a method based on near-infrared spectroscopy combined with partial least squares (PLS) to establish a quantitative model to detect the enantiomeric content of praziquantel in a solution. After the collected spectral information is smoothed by the SG smoothing filter, the second derivative is processed, and the SG(5,5) is comprehensively analyzed in two bands of 1816.9～1884.3nm and 1405.3～1425.4nm, and a good model is established. The detection method can realize rapid and non-destructive detection of samples, has high sensitivity, and can be applied to production workshops. Based on the above detection method, the present invention also provides an infrared spectrum modeling toolkit for determining the enantiomeric composition of praziquantel, comprising: a spectral file access integration module, an image preprocessing module, a band optimization module, and a modeling module and model evaluation modules, and the application of the above toolkits in the field of praziquantel drug analysis. |
| priorityDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.