http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108315350-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y109-03001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-89 |
filingDate | 2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108315350-B |
titleOfInvention | COX5A overexpression/BDNF low expression transgenic mouse model and construction method and application thereof |
abstract | The invention discloses an overexpression COX 5A/low expression BDNF transgenic mouse model and a construction method and application thereof, wherein the construction method comprises the following steps: constructing a transgenic mouse model over expressing COX 5A; constructing a low-expression BDNF transgenic mouse model; the strain with the highest COX5A overexpression and the strain with the lowest BDNF underexpression are bred in cages, and COX5A overexpression/BDNF underexpression double-hybrid mice are obtained from offspring mice. The over-expression COX 5A/low-expression BDNF transgenic mouse model is obtained for the first time, and a new strategy is provided for preparing medicines for preventing or treating brain aging and aging-related diseases. |
priorityDate | 2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 345.