http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108310467-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 |
| filingDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108310467-B |
| titleOfInvention | Assembled cell-derived extracellular matrix membrane composite bone repair material and preparation method and application thereof |
| abstract | The invention provides an assembled cell-derived extracellular matrix membrane composite bone repair material and a preparation method and application thereof. The composite bone repair material is prepared by completely coating a three-dimensional degradable biological scaffold by a sheet acellular matrix membrane under an aseptic condition, freezing the coated three-dimensional degradable biological scaffold for 24 to 48 hours at a temperature of between 20 ℃ below zero and 80 ℃ below zero, and performing freeze-drying treatment to obtain an ECM membrane composite bone repair material; the sheet acellular matrix membrane is a cell-derived extracellular matrix which is generated by in vitro culture of cells and has certain osteogenesis inducing activity after acellular treatment, and the three-dimensional degradable biological scaffold is a biological scaffold which is made of natural polymers, has a three-dimensional porous microstructure and can be completely degraded and absorbed in a human body. The invention has good bone induction capability, further enhances the bone regeneration capability of the composite material, has simple and easy construction method, can be stored for a long time and has wide clinical application potential. |
| priorityDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.