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filingDate 2018-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108310041-A
titleOfInvention The preparation method of ter penoids in a kind of crotons
abstract The invention discloses a kind of preparation methods of ter penoids in crotons.The preparation method includes the following steps:The dry mature kernals of crotons is crushed, with petroleum ether reflux degreasing 3 times, 1 2h every time, medicinal material after degreasing is that 85 95% ethyl alcohol cold soakings extract 13 times with volume fraction, 13 days every time, merges extracting solution, extracting solution is concentrated under reduced pressure to give medicinal extract;By medicinal extract to use petroleum ether, ethyl acetate and water saturated extracting n-butyl alcohol after appropriate water dissolution successively, ethyl acetate portion is obtained;Ethyl acetate portion is detached through silica gel column chromatography, uses volume ratio 50 successively:1、30:1、20:1、10:1 chloroform methanol elution, collects 20:1 elution fraction, concentrates to obtain the final product.The preparation method simple possible of ter penoids, can be enriched with the compound of terpene in crotons provided by the invention, have a variety of effects such as anti-inflammatory, antitumor, anti-oxidant, can be prepared applied to drug as the active component of crotons.
priorityDate 2018-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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