http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108299470-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 |
| filingDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108299470-B |
| titleOfInvention | Preparation method of cefteram pivoxil |
| abstract | The invention relates to a preparation method of cefteram pivoxil, which comprises the following steps: using 7-ACA and 5-methyl tetrazole as initial raw materials, and reacting in H 2 SO 4 Under the action of (3), 7-MTCA is generated; after amino protection of the Aminothiazolic acid Ethyl ester, in AlMe 3 Generating an intermediate I with 7-MTCA under catalysis; the intermediate I and iodomethyl pivalate are subjected to esterification reaction under the action of a phase transfer catalyst and an acid adsorbent, and deamination protection is performed to obtain a target product, namely the cefteram pivoxil. The method has the advantages of mild reaction conditions, high product purity, high yield, stable process and easy amplification, and is suitable for industrial production. |
| priorityDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.