http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108299443-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1694c67de5bd8bd8f4de057c5d96c38 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2018-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bcda4e6eed1a4838c9c96a4af8e928f |
| publicationDate | 2018-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108299443-A |
| titleOfInvention | The First Synthetic Process of Octahydro-5H-Pyrrolo[1,2-A][1,4]diazepine-5-one |
| abstract | The present invention relates to the first synthesis process of octahydro-5H-pyrrolo[1,2-A][1,4]diazepin-5-one. Using DL-proline as the starting material, the carboxyl group is reduced to obtain pyrrolidine-2-methanol, the amino group on the pyrrole ring is protected by benzyl formate, the alcoholic hydroxyl group is converted into an amino group by the Mitsunobu reaction, and then the 3-position substituted propane is introduced by nucleophilic substitution acid methyl ester, removing the protecting group on the amino group, under the action of a condensing agent, amidation and ring closure to obtain the final product octahydro-5H-pyrrolo[1,2-A][1,4]diazepine-5- ketone. |
| priorityDate | 2018-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.