http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108291210-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32651 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-125 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| filingDate | 2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108291210-B |
| titleOfInvention | Methods for producing and purifying nucleic acid-containing compositions |
| abstract | Described herein are improved methods for producing and purifying nucleic acid-containing compositions, such as non-naturally occurring viruses, e.g., recombinant polioviruses, that can be used as oncolytic agents. Some of the described improved methods relate to improved methods for producing viral DNA templates. Also described are improved methods for chromatographic purification of nucleic acid-containing compositions, wherein nucleic acids in a chromatographic fraction are quantified using a rapid detection method of one or more nucleic acid sequences of the nucleic acid-containing composition, such as by real-time RT-qPCR detection. In addition, improved methods for producing and purifying oncolytic polioviruses, such as PVS-RIPO, are described. Compositions produced using these methods are also provided. |
| priorityDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 174.