Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_872dd7cd609eb2a937dcfd303d521798 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-00051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-10051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16051 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02 |
filingDate |
2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db13e3fe50818c6371f92ea5eae8a2c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797477689514b94f0ee22a875cbf1fd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ea7a34bc17bff739bf31705bda07354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e8f6856fb0a62109a92ecabb19373b5 |
publicationDate |
2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-108291208-A |
titleOfInvention |
Stable cell lines for production of retroviruses |
abstract |
The present invention relates to cells producing retroviruses comprising nucleic acid sequences encoding: gag and pol proteins; envelope proteins or functional substitutes thereof; and the RNA genome of retroviral vector particles, wherein said nucleic acid sequences are all located in A single locus within the genome of a cell that produces retroviruses. The present invention also relates to a nucleic acid vector comprising a non-mammalian origin of replication capable of maintaining at least 25 kilobases (kb) of DNA, characterized in that said nucleic acid vector comprises a protein encoding gag and pol, and an env protein or a functional substitute thereof Retroviral nucleic acid sequence. The invention also relates to uses and methods of using said nucleic acid vectors to generate stable retroviral packaging and production cell lines. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113528515-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113528515-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112430582-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112430582-A |
priorityDate |
2015-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |