http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108283717-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f347d94f0db9282af2f687ecf86b6bb7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 |
| filingDate | 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee9ca01cbbbeef4c518fab568ae22eb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_244ef0092032d7a1c9d5941ed4ae19d3 |
| publicationDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108283717-A |
| titleOfInvention | The exploitation and application of humanization or full people source Notch4 acceptor monoclonal antibody drugs |
| abstract | The exploitation and application of humanization or full people source Notch4 acceptor monoclonal antibodies.Notch4 unconventionality expressions in some specific pathological tissues, the very high expression especially in many tumour cells such as liver cancer cells, and oncogene effect is played, show that Notch4 receptors can be used as drug target.Therefore there will be very important clinical value with Notch4 monoclonal antibodies to develop corresponding antibody target medicine or reagent for clinical diagnosis.At present still without the humanization for being directed to Notch4 or full human monoclonal antibody.The present invention announces the exploitation of humanization or full people source Notch4 monoclonal antibodies for the first time, and using this Notch4 monoclonal antibody as therapeutic antibodies drug, or is pharmaceutical carrier and various bioactive molecules（Such as chemotherapeutics, radiopharmaceutical, diagnostic flag）Coupling builds various humanizations or full people source Notch4 antibody target medicines or antibody diagnosis label, is used for the treatment and diagnosis of relevant disease.This has very important clinical value for the prevention and treatment of relevant disease. |
| priorityDate | 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 863.