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filingDate 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108276522-B
titleOfInvention Preparation method of iron ion double-crosslinked alginate-polyacrylamide acrylic acid high-performance hydrogel capable of being printed in 3D mode
abstract The invention discloses a preparation method of iron ion double-crosslinking alginate-polyacrylamide acrylic acid high-performance hydrogel capable of being printed in a 3D mode. Firstly, uniformly mixing sodium alginate, acrylamide, acrylic acid and a photoinitiator, performing in a mold or 3D printing mode, and irradiating under an ultraviolet lamp to copolymerize an AAc monomer and an AM monomer. Soaking the hydrogel scaffold in Fe after polymerization 3+ Ionic crosslinking is formed in the solution, and finally the solution is soaked in deionized water for balancing to remove unreacted monomers. Both networks are Fe 3+ And crosslinking is carried out, so that common crosslinking points are arranged between the two networks, and the hydrogel has excellent performance. In addition, the sodium alginate is natural polymer and has good biocompatibility, and the viscosity is adjusted by adding a small amount of viscosity regulator in a sol state, so that the sodium alginate has good collapse resistance and rapid gelation characteristics, and the hydrogel can be prepared into various compounds with high porosity by using a 3D printing technologyHeterostructured hydrogels.
priorityDate 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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