http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108276440-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662 |
| filingDate | 2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108276440-B |
| titleOfInvention | It is a kind of can the antiviral slow releasing pharmaceutical and the preparation method and application thereof that uses of intraocular injection |
| abstract | The present invention provide it is a kind of can the antiviral slow releasing pharmaceutical and the preparation method and application thereof that uses of intraocular injection.The drug is phosphonic acid difficulty soluble salt micro-crystal, and the phosphonic acid difficulty soluble salt is the multivalent metal salt of phosphonic acid.The preparation method comprises the following steps: reacting phosphonic acid monovalent metal salt in water with the soluble salt of polyvalent metal, the system of the micro-crystal of difficulty soluble salt containing phosphonic acid is obtained.The present invention delays the particular/special requirement of controlled release for intraocular injection, has designed and developed phosphonic acid difficulty soluble salt micro-crystal slow-releasing system, and nominal drugloading rate can be higher than 100%.Phosphonic acid difficulty soluble salt micro-crystal slow releasing pharmaceutical in the vitreous chamber of lagophthalmos can lasting stability sustained release, the concentration of phosphonic acid root maintains the effective treatment concentration of Foscarnet sodium or more always in vitreous chamber, the period is sustained up to 12 weeks, and the drug does not have overt toxicity reaction and inflammatory reaction.The phosphonic acid difficulty soluble salt should can be used as it is a kind of can in vitreous chamber the injection slow release method of antiviral drugs carry out using. |
| priorityDate | 2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.