http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108276435-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1098 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-109 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108276435-B |
| titleOfInvention | Process for the preparation of intermediates useful in the preparation of compounds that specifically bind to β amyloid |
| abstract | A process for preparing an intermediate useful for preparing a compound that specifically binds to β amyloid, wherein the intermediate useful for preparing a compound that specifically binds β amyloid is represented by structural formula II: the preparation method of the intermediate comprises the following steps: generating 2- (4-aminobenzene) -6-bromobenzothiazole from 2- (4-nitrobenzene) -6-bromobenzothiazole through reduction reaction; adding 2- (4-aminobenzene) -6-bromobenzothiazole into formaldehyde to react to generate 2- (4-methylaminobenzene) -6-bromobenzothiazole; adding 2- (4-methylaminobenzene) -6-bromobenzothiazole into diboron pinacol ester to react to generate 2- (4-methylaminobenzene) -6-boronic acid pinacol ester benzothiazole; oxidizing 2- (4-methylaminobenzene) -6-boronic acid pinacol ester by using an oxidizing agent to obtain 2- (4-methylaminobenzene) -6-dihydroxy boronobenzothiazole shown in the structural formula I. |
| priorityDate | 2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.