| abstract |
The invention discloses a composite bone cement, a preparation method and application thereof, and a bone repair material, wherein the composite bone cement is prepared by mixing raw materials comprising 50-80% of solid phase powder and 20-50% of curing liquid according to mass percentage, the solid phase powder comprises phosphate and/or acid phosphate, and the curing liquid comprises chitosan, hyaluronic acid, organic acid and water. The composite bone cement has good injectability, bioactivity, bone conduction and repair capacity, the bone repair material obtained by curing has good mechanical property, the surface of the bone repair material is easy to adhere to cells, and the differentiation capacity of the cells can not be influenced. |