http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108273058-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
| filingDate | 2018-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108273058-B |
| titleOfInvention | A kind of tumor targeted therapy sustained-release preparation and preparation method thereof |
| abstract | The invention provides a preparation method of a tumor targeted therapy sustained-release preparation, which comprises the steps of: (1) mixing titanium powder, aluminum powder and graphite powder for ball milling and pressing, and under the condition of passing argon gas, performing high temperature Sintering to obtain Ti 3 AlC 2 ceramic material; (2) crushing the product obtained in step (1) into powder, placing it in hydrofluoric acid for reaction, after centrifugal washing, placing it in an aqueous solution of tetrapropylammonium hydroxide for reaction, centrifuging, Wash to obtain Ti 3 C 2 MXenes material; (3) drop the aqueous solution of Ti 3 C 2 MXenes material into the mixed aqueous solution of CTAC and TEA to react; then add TEOS, react at 80°C, centrifuge and wash to obtain mesoporous oxidation Silicon-encapsulated MXene nanosheets; (4) surface modification of the compound in step (3) with polyethylene glycol, and then covalently binding with RGD polypeptide to load the drug, and the result is obtained. The present invention can realize targeted therapy for tumors and obtain good tumor suppressing effect. |
| priorityDate | 2018-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.