| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad23ecf473f76fdb0ed90e87ed0e312f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-04005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_902a3374b3c1e97ade4f44ab716ed09d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82bfe5be91ec9fe27910ecff5f1bc597
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fabb447e86b48cc05e310771f5f631e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_282eded036195e5f999634e43697b19b |
| publicationDate |
2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108271384-A |
| titleOfInvention |
Genomic sequence conversion method of Gram-positive bacteria for specific conversion of nucleic acid bases targeting DNA sequences, and molecular complex used therefor |
| abstract |
The present invention is a method for modifying the target site of the double-stranded DNA possessed by Gram-positive bacteria, which includes: making the target nucleotide sequence in the double-stranded DNA selected by nucleic acid base conversion enzyme The complex formed by the combination of specific binding nucleic acid sequence recognition modules contacts the double-stranded DNA, does not cut at least one strand of the double-stranded DNA in the targeting site, and makes one of the targeting sites The above nucleotides are deleted or converted into other 1 or more nucleotides, or the step of inserting 1 or more nucleotides into the target site, the contact between the double-stranded DNA and the complex, through the The Gram-positive bacterium introduces the nucleic acid encoding the complex. The present invention also provides a complex for use in the method, the complex consisting of a nucleic acid sequence recognition module that specifically binds to a target nucleotide sequence in double-stranded DNA possessed by Gram-positive bacteria, and a nucleic acid base Combined enzymes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110343689-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110343689-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112585266-A |
| priorityDate |
2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |