http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108254346-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1466 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108254346-B |
| titleOfInvention | Magnetic fluorescent copolymer nano probe with DNA as template and application thereof |
| abstract | The invention relates to a magnetic fluorescent copolymer nano probe taking DNA as a template, which comprises a linear template DNA chain, wherein the template DNA chain is respectively connected with magnetic nanoparticles with super-paramagnetic property, quantum dot nanoparticles with fluorescent property and DNA or RNA aptamers capable of specifically identifying tumor cells by means of a recognition DNA sequence, and the magnetic nanoparticles or the quantum dot nanoparticles and the DNA or RNA aptamers are alternately connected on the template DNA chain. The invention also discloses application of the magnetic fluorescent copolymer nano probe in preparation for identifying circulating tumor cells. The nano probe can amplify magnetic signals and fluorescent signals, has high specificity selection on tumor cells, and has low non-specific adsorption on normal blood cells. |
| priorityDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.