| abstract |
The invention discloses a slightly acidic environment, photothermal responsive drug carrier MXene nanosheet and its preparation method. The preparation method of the nanosheet includes the following steps: (1) mixing titanium powder, aluminum powder and graphite powder for ball milling, Pressing, sintering at high temperature under the condition of feeding argon to obtain Ti 3 AlC 2 ceramic material; (2) breaking the result of step (1) into powder, placing it in hydrofluoric acid for reaction, and then centrifuging and washing Afterwards, placed in tetrapropylammonium hydroxide aqueous solution to stir the reaction, then centrifuged and washed to obtain the Ti 3 C 2 MXenes material; (3) drop the Ti 3 C 2 MXenes material aqueous solution into the mixed aqueous solution of CTAC and TEA, Carry out the reaction; add TEOS, carry out the reaction at 80°C, centrifuge and wash to obtain the product. The nanosheet obtained in the present invention has ideal drug-loading ability and has acidity responsiveness and near-infrared photothermal stimulation responsiveness, and can be used as an excellent drug carrier for corresponding purposes. |