http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108245516-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2017-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108245516-B |
| titleOfInvention | A kind of pharmaceutical composition and preparation method thereof containing rosuvastain calcium |
| abstract | The pharmaceutical composition and preparation method thereof containing rosuvastain calcium that the invention discloses a kind of.The pharmaceutical composition includes: 1 part of rosuvastain calcium, 8-16 parts of filler, 0.4-1.2 parts of disintegrating agent, 0.05-0.20 parts of magnesia, and 0.15-0.30 parts and lubricant 0.1-0.5 parts of glidant；Wherein, partial size≤100 μm D90 of rosuvastain calcium.The dosage of stabilizer or pH adjusting agent in pharmaceutical composition of the invention is low, and the stability of the pharmaceutical composition and dissolution rate are good, and the dissolution curve stability of product is good, and the uniformity of product and API are high.Preparation method of the invention avoids the introducing of water by dry granulation, reduces production energy consumption, while also assuring the stability of product. |
| priorityDate | 2017-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.