http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108239668-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6813 |
filingDate | 2018-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108239668-B |
titleOfInvention | Label-free DNA mass spectrum quantitative analysis method based on exonuclease III auxiliary target cyclic amplification |
abstract | The invention discloses a label-free DNA mass spectrum quantitative analysis method based on exonuclease III auxiliary target cyclic amplification. The method combines an exonuclease III auxiliary target cyclic amplification strategy, a mass spectrum and a spectrum deformation quantitative theoretical model together, and can realize sensitive and accurate quantitative analysis of target DNA in a complex biological sample. Meanwhile, the method overcomes the defects of the existing method for identifying the single nucleotide polymorphism, and the strategy provided by the invention can definitely identify the single nucleotide polymorphism by utilizing the capacity of identifying different residual DNA fragments of mass spectrum. |
priorityDate | 2018-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.