http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108236603-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-787 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-787 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108236603-B |
| titleOfInvention | Pyrrole imidazole polyamide liposome and preparation method and application thereof |
| abstract | The invention provides a pyrrole imidazole polyamide liposome, a preparation method and application thereof, and particularly discloses a pyrrole imidazole polyamide liposome which is composed of a lipid bilayer and pyrrole imidazole polyamide entrapped in the lipid bilayer, wherein the lipid bilayer comprises phospholipid molecules and cholesterol, the molar ratio of the phospholipid molecules to the cholesterol is (3-4): 1, and the molar ratio of the phospholipid molecules to the pyrrole imidazole polyamide is (20-30): 1. The pyrrole imidazole polyamide liposome provided by the invention uses the cavity in the liposome to encapsulate pyrrole imidazole polyamide, and compared with the encapsulation mode of other carriers, the encapsulation capacity can be effectively improved, so that the bioavailability of pyrrole imidazole polyamide drugs is remarkably improved. |
| priorityDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.