http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108218989-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108218989-B |
titleOfInvention | anti-PD-1 nano antibody PD-1/Nb18 and preparation method and application thereof |
abstract | The invention discloses an anti-PD-1 nano antibody PD-1/Nb18 and a preparation method and application thereof. The nano antibody PD-1/Nb18 provided by the invention comprises an antigenic determinant complementary region and a framework region; the antigenic determinant complementary region of the nano antibody PD-1/Nb18 consists of CDR1, CDR2 and CDR 3; through the nano antibody PD-1/Nb18 nucleotide sequence and the host cell disclosed by the invention, the nano antibody PD-1/Nb18 can be efficiently expressed in escherichia coli, is applied to the research and development of a PD-1 molecular detection reagent, and is used for preparing a tumor inhibitor or a tumor cell inhibitor and preparing a medicine for inhibiting PD-1 activity and promoting T cell proliferation. |
priorityDate | 2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.