http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108218987-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 |
filingDate | 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108218987-B |
titleOfInvention | High-affinity, high specific, more antigen recognizing epitopes the anti-human CTLA4 antibody with higher function |
abstract | The present invention disclose a kind of high-affinity, high specific, more antigen recognizing epitopes the anti-human CTLA4 antibody with higher function.CTLA4 monoclonal antibody of the invention be capable of specificity with CTLA4 ining conjunction with, and the combination of CTLA4 and B7 albumen can be effectively blocked, specifically the immune negative regulator of releasing CTLA4, activation T cell secrete cytokines.Above-mentioned function meets or exceeds the level of unique CTLA4 targeted drug Yervoy currently on the market, and the epitope for having partial antibody to be different from Yervoy, has bigger diversity. |
priorityDate | 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 383.