http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108218875-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78a3923fe454ed134b9d259d07ecea8b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate | 2017-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18a0f490c29eb653c07ff346aa2f2be9 |
publicationDate | 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108218875-A |
titleOfInvention | Pyrimido-pyrimidine diones CDK4/6 kinase inhibitors and its application |
abstract | The invention belongs to chemical medicines, it is related to pyrimido-pyrimidine diones CDK4/6 kinase inhibitors and its application, pyrimido-pyrimidine diones CDK4/6 kinase inhibitors compound shown in formula I or its pharmaceutically acceptable salt, and the pharmaceutical composition containing these compounds and application of these compound or compositions in medicine preparation, pyrimido-pyrimidine cyclohexadione compounds provided by the invention have preferable inhibitory activity to CDK4 and CDK6 kinases, breast cancer cell is significantly inhibited, Tumor incidence can effectively be reduced, extend tumor patient life, |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022072336-A1 |
priorityDate | 2017-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.