http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108218762-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-36 |
| filingDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108218762-B |
| titleOfInvention | Synthetic method of 2-quaternary carbon indole-3-ketone compound |
| abstract | The invention relates to a method for synthesizing 2-site quaternary carbon indole-3-ketone compounds with high efficiency and simple operation. The method takes peroxide as an oxidant, utilizes 2-substituted indole and indole compounds to carry out intermolecular reaction, namely, adds substrate 2-substituted indole and indole compounds into a reaction bottle filled with the oxidant and a solvent, carries out reaction for 1-48 h in an oil bath at 60-140 ℃, cools to room temperature after the reaction is finished, adds saturated sodium bicarbonate to carry out quenching reaction, and then carries out extraction, separation and concentration to obtain the product 2-quaternary carbon indole-3-ketone compound, wherein the yield is up to 96 percent. |
| priorityDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.