http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108210508-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78a3923fe454ed134b9d259d07ecea8b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 |
filingDate | 2017-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2236591dcba38af318b6e226c2e6b4e |
publicationDate | 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108210508-A |
titleOfInvention | A kind of antineoplastic pharmaceutical compositions |
abstract | A kind of antineoplastic pharmaceutical compositions provided by the invention, include active constituent and pharmaceutically acceptable auxiliary material, it is characterised in that:The active constituent is made of the CDK4/6 kinase inhibitors shown in gemcitabine and Formulas I or its pharmaceutically acceptable salt, and gemcitabine and the mass ratio of CDK4/6 kinase inhibitors or its pharmaceutically acceptable salt are (2 8) in the active constituent:1.The pharmaceutical composition anticancer therapeutic is good, toxic side effect is low;Since CDK4/6 kinase inhibitors are to the sensibility of gemcitabine, the two drug combination produces synergistic effect, so as to reduce the Clinical practice dosage of capecitabine, it reduces large dosage and uses toxic side effect caused by capecitabine, safety clinical treatment index is improved, there is preferable potential applicability in clinical practice. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110143948-A |
priorityDate | 2017-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.