http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108210497-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
filingDate 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108210497-B
titleOfInvention Application of compound MLN4924 in preparation of bunyaviridae phlebovirus inhibitor
abstract The invention discloses an application of a compound MLN4924 in preparing a bunyaviridae phlebovirus inhibitor, wherein the compound MLN4924 has a structure shown in a formula (I): experiments prove that the compound MLN4924 can inhibit the fever-associated thrombocytopenia syndrome virus or Sicily phlebovirus in phlebovirus of bunyaviridae. The invention can activate interferon antiviral approach when host cell is infected by virus by inhibiting RIG-I ubiquitination degradation mediated by SFTSV NSs, and obviously inhibit virus replication and proliferation.
priorityDate 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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