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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6855
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-06
filingDate 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108192955-B
titleOfInvention Low-frequency mutation DNA fragment detection method and library establishment method
abstract The invention belongs to the technical field of genetic engineering, and particularly relates to a low-frequency mutation DNA fragment detection method and a library establishment method. By adopting the hybrid capture and molecular label technology and combining a special library construction mode, the invention solves the technical problems of low efficiency of capturing DNA fragments, introduction of error mutation in the library construction process, low detection limit and low sensitivity in the prior detection technology, improves the specificity of the library, reduces the false positive rate and improves the utilization rate of the template.
priorityDate 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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