http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108192879-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
filingDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108192879-B |
titleOfInvention | Preparation and application of finless eel aldone reductase mutant protein |
abstract | The invention discloses preparation and application of finless eel aldehyde ketone reductase mutant protein, and belongs to the technical field of functional gene mutation and application in aquatic biotechnology. The aldone reductase mutant protein is the mutation of A81K site of eel Eakr gene, namely, the base corresponding to the 81 th amino acid of the eel Eakr gene is mutated into AAG from GCT, and the corresponding amino acid is mutated into lysine from alanine. The invention provides important reference data for deeply knowing the function of the finless eel aldehyde ketone reductase Eakr and the function of the catalytic quadruplet on substrate recognition, identifies the activity of the mutant protein and the function in inhibiting the generation of inflammatory factors, and provides a technical method for further exploring the function of the finless eel aldehyde ketone reductase. |
priorityDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 353.