http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108192595-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-7773
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00
filingDate 2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108192595-B
titleOfInvention Magnetic-up-conversion nanoparticle aggregate and preparation method thereof
abstract The invention discloses a magnetic-up-conversion nanoparticle aggregate, which is prepared by the following method: under the protection of nitrogen, uniformly mixing an oleic acid modified magnetic nanoparticle chloroform solution and an oleic acid modified up-conversion nanoparticle chloroform solution according to a mass ratio of 4:1-1: 10; adding dodecyl trimethyl ammonium bromide water solution, and stirring for 5-15 minutes at 35-45 ℃; then adding 0.2g of polyvinylpyrrolidone and 4.0-10.0mL of glycol, stirring for 3-8 hours at 75-85 ℃, and cooling to room temperature; and (4) centrifuging and washing to obtain the magnetic-up-conversion nano particle aggregate. The preparation method is simple and convenient, has good repeatability, and can realize accurate regulation and control of the content, the size, the superparamagnetism and the up-conversion luminescence performance of each component of the magnetic-up-conversion nanoparticle aggregate by adjusting the reaction parameters such as the proportion of the magnetic nanoparticles to the up-conversion nanoparticles and the addition amount of ethylene glycol; can simultaneously meet the application requirements of biological separation, biological imaging, biological detection, magnetic heat treatment and the like.
priorityDate 2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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