http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108191994-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-722 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-722 |
| filingDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108191994-B |
| titleOfInvention | Chitosan derivative with selective antibacterial property and preparation method thereof |
| abstract | The invention discloses a chitosan derivative with selective antibacterial property and a preparation method thereof. The invention firstly discloses a molecular structural formula of the chitosan derivative as shown in formula (1): wherein x, y and z are natural numbers, x is more than or equal to 1, y is less than or equal to 10000, and R is 1 Is a basic amino acid or an oligomer thereof, R 2 Is a hydrophobic amino acid or an oligomer thereof. The invention further discloses a preparation method of the chitosan derivative. The chitosan derivative of the invention grafts the basic amino acid or the oligomer thereof and the hydrophobic amino acid or the oligomer thereof on the chitosan main chain at the same time, the chitosan derivative has certain selectivity on the inhibition effect of candida albicans and lactobacillus by regulating and controlling the proportion of the basic unit and the hydrophobic unit, and the inhibition rate of the chitosan derivative on the lactobacillus is higher than or equal to 90 percent when the inhibition rate of the chitosan derivative on the candida albicans is higher than or equal to 90 percent<50 percent, and the whole preparation process is energy-saving and environment-friendly and can be industrialized on a large scale. |
| priorityDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.