http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108191838-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-948 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108191838-B |
titleOfInvention | Half cyanines class fluorescence probe and its preparation method and application for detecting carboxypeptidase y |
abstract | The present invention relates to the detection fields of carboxypeptidase y, and in particular to the half cyanines class fluorescence probe and its preparation method and application for detecting carboxypeptidase y.Half cyanines class fluorescence probe and preparation method thereof is disclosed, which has the structure of formula (1), wherein using tertiary amyl as the recognition group of carboxypeptidase y;Its synthetic method includes: that in organic solvent, formula (2) compound is contacted with pivaloyl chloride in the presence of necleophilic reaction condition and acid binding agent.The application and the active method of detection carboxypeptidase y and detection kit that the invention also discloses the probes in the activity of detection carboxypeptidase y.Half cyanines class fluorescence probe of the invention is for related with carboxypeptidase y Activity determination in application, high sensitivity, good, fluorescence intensity the variation of selectivity are easy to detect greatly, and stability is higher, using more convenient, price is less expensive. |
priorityDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.