http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108191770-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 |
| filingDate | 2018-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108191770-B |
| titleOfInvention | 2, 3-phthalazinone or 2, 3-naphthyridine derivatives and uses thereof |
| abstract | The invention relates to the technical field of chemical synthetic drugs, in particular to a 2, 3-phthalazinone or 2, 3-phthalazinone derivative of a PARP and HDACs double-target inhibitor and application thereof. Book (I)The technical problem to be solved by the invention is to provide a novel 2, 3-diazanaphthalene ketone derivative or 2, 3-diazanaphthol derivative of a PARP and HDACs double-target inhibitor. The structure of the compound is shown as a formula I or a formula II. The compound of the invention has obvious inhibitory activity of poly (adenosine diphosphate ribose) polymerase and histone deacetylase, has effective anti-tumor effect, and provides a new choice for the development and application of anti-tumor drugs related to the inhibitory activity of poly (adenosine diphosphate ribose) polymerase and histone deacetylase. |
| priorityDate | 2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.