http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108191762-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-22 |
| filingDate | 2018-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108191762-B |
| titleOfInvention | Extraction method of huperzia serrata extract without heavy metal |
| abstract | A method for extracting pure natural and heavy metal-free huperzia serrata extract comprises the following steps: (1) pretreatment and extraction: picking and crushing the huperzia serrata raw material, adding an acidic extraction solvent for continuous countercurrent extraction, cooling and filtering; (2) purifying with macroporous adsorption resin: adjusting to alkalinity, filtering, adsorbing the filtrate with macroporous adsorbent resin column, washing with water to remove the eluate, eluting with alcohol water solution and collecting the eluate, washing with water and collecting the eluate to obtain mixed eluate; (3) purifying by using cation exchange resin: loading onto cation exchange resin chromatographic column, washing with water, and collecting effluent; (4) concentrating and drying: concentrating under reduced pressure, and drying. In the product obtained by the method, the removal rate of heavy metals is more than or equal to 99.97 percent, the mass content of huperzine A is more than or equal to 2.3 percent, and the total yield is more than or equal to 95.5 percent; the method has the advantages of simple process, low cost and good selectivity, and is suitable for industrial production. |
| priorityDate | 2018-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.