| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2bfd42b26234dd52d0ca354a643650e8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-74 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-52 |
| filingDate |
2018-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76f9da37e5078a89bba095a5dba2d67b |
| publicationDate |
2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108191674-A |
| titleOfInvention |
A kind of synthetic method of benzidine compound |
| abstract |
The invention discloses a method for synthesizing benzidine compounds. Compound (I) obtains compound (II) through catalytic coupling reaction; compound (II) obtains compound (III) through alkaline or acidic hydrolysis reaction process; compound (III) obtains through catalytic hydrogenation reduction reaction in an organic system benzidine compound (V); or compound (II) is obtained by catalytic hydrogenation reduction in an organic solvent to obtain compound (V), and compound (V) is subjected to alkaline or acidic hydrolysis to obtain compound (IV). The method disclosed by the invention overcomes many disadvantages of the existing methods, uses conventional commercially available catalysts, greatly shortens the reaction time and improves the production capacity. It is worth mentioning that the organic solvent of the present invention can be recycled and applied mechanically, and the hydroiodic acid or hydrobromide produced by the coupling reaction can be successfully converted into iodide or bromide salt with high economic value after treatment. Therefore, the disclosed method is an economical green method that is easy to industrialize. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113668090-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022199226-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114478291-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115108918-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115108918-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113668090-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110105568-A |
| priorityDate |
2018-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |