http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108181419-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-89 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-89 |
filingDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108181419-B |
titleOfInvention | Detection method of diethyl naphthalene cholamine raw material or preparation related substances thereof |
abstract | The invention discloses a detection method of a naphthalene disulfonic acid ethyol cholamine raw material or related substances of a preparation thereof, which comprises the following steps: the reversed-phase high performance liquid chromatography of a reversed-gradient post-column compensation mode is adopted, octadecylsilane chemically bonded silica is used as a chromatographic column filler, an electric spray detector (CAD) is adopted, and volatile negative ions are selected to elute a mobile phase of the reagent. The detection method has strong specificity, high sensitivity, higher precision and accuracy and good durability, is suitable for the inspection and quality control of the related substances of the raw material of the diethylcholammonium naphthalene sulfonate or the preparation thereof, can accurately reflect the content of the related substances in the raw material of the diethylcholammonium naphthalene sulfonate or the preparation thereof, and provides reasonable basis for the formulation of quality standard so as to better control and master the quality of the product, thereby improving the safety of clinical medication. |
priorityDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.