http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108181385-A

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02
filingDate 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bde9dc0a8001aa79b2f976b1be9f9def
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publicationDate 2018-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108181385-A
titleOfInvention Method that is a kind of while detecting the enantiomter of crystal methamphetamine and amphetamine in liquid biological sample
abstract The present invention provides a kind of methods for detecting R () crystal methamphetamine in liquid biological sample, S (+) crystal methamphetamine, R () amphetamine and S (+) amphetamine simultaneously, include the following steps:(1) sample pre-treatments:At room temperature, liquid biological sample sample is taken, is placed in an EP pipes, and add in inner mark solution;Implement first time vortex oscillation, be then centrifuged for, supernatant taken to be placed in another EP pipes, and add in methanol;Implement second of vortex oscillation, finally, sample introduction to LC MS/MS systems;(2) LC MS/MS are analyzed.Method of the present invention has excellent selectivity, linear dependence, preci-sion and accuracy, LOD and LOQ is sufficiently low simultaneously, therefore, it is very suitable for the chiral separation and measure of crystal methamphetamine and the respective enantiomter of amphetamine in blood, urine, success is speculates that drug source and the illegal abuse of correct differentiation and clinical application provide technical support, so as to have considerable market potential.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114689757-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110907542-A
priorityDate 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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