http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108178720-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-263 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-35 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-18 |
filingDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108178720-B |
titleOfInvention | A kind of synthetic method of 4-cyclobutylbiphenyl fluorine-containing compound |
abstract | The invention discloses a method for synthesizing 4-cyclobutylbiphenyl fluorine-containing compounds. The p-chlorohalobenzene is used as an initial raw material, and the Grignard reaction is carried out to generate it; the coupling reaction with cyclobutanone generates cyclobutanol chlorobenzene; and the dehydration reaction is carried out. Cyclobutene chlorobenzene is generated; 4-cyclobutenyl benzene boronic acid is generated by one-pot reaction; 4-cyclobutenyl biphenyl fluorine-containing compound is generated by coupling reaction with fluorine-containing halogenated benzene; 4-cyclobutenyl biphenyl is obtained by hydrogenation reaction The butyl biphenyl fluorine-containing compound IX has the characteristics of high conversion rate, low cost, safe and stable process, short reaction steps, green process route and less pollutant discharge. |
priorityDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.