http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108164520-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-147 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147 |
filingDate | 2018-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108164520-B |
titleOfInvention | Coupling compound of hypoxia inhibitor and antitumor drug, preparation and application thereof |
abstract | The invention provides a coupling compound formed by the reaction of a hypoxia inhibitor and an antitumor drug, wherein the antitumor drug is glutathione mercaptotransferase inhibitor NBDHEX, a marketed antitumor drug irinotecan and a marketed antitumor drug gemcitabine, and the structural formula of the coupling compound is shown as formula I, formula II and formula III respectively; the invention also provides a preparation method of the coupling compound and application of the coupling compound in preparation of antitumor drugs. |
priorityDate | 2018-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 196.