http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108164483-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-92 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B37-04 |
| filingDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108164483-B |
| titleOfInvention | Novel five-membered aromatic heterocycle and aromatic ring and five-membered aromatic heterocycle arylation synthesis method |
| abstract | The invention belongs to the technical field of organic synthesis, and particularly relates to an arylhydrazine derivative which is used as a novel arylation reagent and participates in an arylation synthesis method of five-membered aromatic heterocycle or aromatic ring and five-membered heterocycle. The method comprises the following steps: adding raw materials and aryl hydrazide into a reactor, and reacting for 8-24h at 60-100 ℃ under the condition of adding an oxidant and a transition metal catalyst. And after the reaction is finished, carrying out suction filtration, extracting the filtrate by using ethyl acetate, drying to obtain a crude product of the target compound, and carrying out silica gel column chromatography to obtain a pure product of the target compound. The arylation preparation method of the five-membered aromatic heterocycle or the aromatic ring and five-membered heterocycle provided by the invention is scientific and reasonable, and has the advantages of simple and convenient operation, higher yield, easy amplification and purification and the like. |
| priorityDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.