http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108159008-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 |
filingDate | 2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108159008-B |
titleOfInvention | Preparation method of valsartan chewable tablet |
abstract | The invention provides a preparation method of a valsartan chewable tablet, which comprises the following components in parts by weight: 8 parts of valsartan; 20-24 parts of poloxamer; 10-15 parts of microcrystalline cellulose; 10-15 parts by weight of pregelatinized starch; 15-18 parts of lactose; 15-20 parts of mannitol; 6-9 parts of cane sugar; 2-4 parts of aspartame; 1-3 parts of sweet orange powder essence; 2-4 parts of micro silica gel powder; 1-2 parts of magnesium stearate. According to the preparation method of the valsartan chewable tablet, the water solubility of valsartan can be improved by adjusting the components and the mixture ratio of the components, and the problems of large tablet weight difference, loose tablets, sticking and the like in the production process of the valsartan tablet are solved; meanwhile, the bitter and astringent feeling of the medicine can be improved, so that the medicine can be directly chewed and taken by patients without water, and the convenience and the compliance of the medicine taking of the patients are greatly improved. |
priorityDate | 2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.