http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108152275-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-76 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 |
filingDate | 2017-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108152275-B |
titleOfInvention | A kind of hyaluronic acid enzyme assay method based on electrochemiluminescsystem system |
abstract | The invention discloses a kind of hyaluronic acid enzyme assay method based on electrochemiluminescsystem system is hydrated three (2,2- bipyridyl) chlorination ruthenium systems by hyaluronic acid-six, constructs one for detecting the electrochemiluminescsystem system of hyaluronidase.Hyaluronidase can carry out endonuclease reaction to hyaluronic acid, and the hyaluronic acid fragments after digestion can be entered in ultrafiltrate together with six three (2, the 2- bipyridyl) ruthenic chlorides of hydration of Electrostatic Absorption on hyaluronic acid fragments by centrifugal ultrafiltration.Therefore in the presence of hyaluronidase, the amount that the luminescent substance six in ultrafiltrate is hydrated three (2,2- bipyridyl) ruthenic chlorides be will increase, and the electrochemical luminescence intensity of luminescence system can enhance, and the detection to hyaluronidase concentration may be implemented based on this.The method of the present invention raw material is easy to get, is easy to operate, time-consuming shorter and high sensitivity, is expected to the fields such as to detect in life science and clinical medicine and be used widely. |
priorityDate | 2017-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.