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filingDate 2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cacf4ebb44940690d2966090db46e897
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publicationDate 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108148118-A
titleOfInvention A kind of separation and purification method of cyclosporin H
abstract A method for separating and purifying cyclosporin H, wherein the chromatographic column adopts phenylcarbamate-based β-cyclodextrin silica gel as the packing material of the chromatographic column to carry out the separation and purification of cyclosporin H, which can Cyclosporin A and cyclosporin H in the raw material are effectively separated. At the same time, in the separation and purification process, a single polar solvent can be used, the solvent can be recycled, and the production cost can be saved. During the elution process, the cross section containing cyclosporin H can be recovered and repurified to avoid waste. At the same time, the technical solution is applicable to various cyclosporine H-containing raw materials, has strong applicability, can be prepared in large quantities, and can provide a large amount of high-purity cyclosporine H raw materials for the pharmaceutical industry.
priorityDate 2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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