http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108147973-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 |
| filingDate | 2017-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108147973-B |
| titleOfInvention | Preparation method of N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine |
| abstract | The invention provides a preparation method of N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine. The preparation method comprises the following steps: under the action of a first catalyst, carrying out addition reaction on a compound 1 and a compound 2 to obtain an addition product, wherein the first catalyst is selected from a first thiourea compound and/or a urea compound; and hydrogenating the addition product to obtain N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine. The addition of the first catalyst (the first thiourea compound and/or the urea compound) in the reaction system is beneficial to improving the selectivity of the addition reaction, improving the separation efficiency of the product required in the addition reaction process and further improving the yield of the final product N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine. The method has the advantages of short synthetic route, simple post-treatment, applicability to industrial production and the like. |
| priorityDate | 2017-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.